Wissenschaftliche Publikationen "Mikrofluidik + Bioanalytik"

This project took place in cooperation with Organska Elektronika d.o.o. and the International Iberian Nanotechnology Laboratory (INL). The company Organska Elektronika d.o.o. is developing a new system for the detection of myco-toxin in food i.e. milk. The main goals of this project were the development of a plastic catridge and the development of a portable incubator. The catridge was designed for its functionality with a simple microfluidic circuit. The middle part of the catridge can be produced by injection molding for high-volume production. Several sealing methods for the fluidic circuit were introduced. In addition a portable incubator was developed for the simultaneous use of four catridges.

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The presence of endocrine disruptors in surface waters can have negative implications on wildlife and humans both directly and indirectly. A molecularly imprinted polymer (MIP) was explored for its potential to enhance the UV-Vis determination of trenbolone in water using solid phase extraction (SPE). The synthesized MIP was studied using Fourier transform infrared spectra (FTIR) and scanning electron microscopy (SEM). Using the MIP resulted in a preconcentration and enrichment factor of 14 and 8, respectively. Trenbolone binding on the MIP was shown to follow a Langmuir adsorption and had a maximum adsorption capacity of 27.5 mg g-1. Interference studies showed that the MIP selectivity was not compromised by interferences in the sample. The MIP could be recycled three times before significant loss in analyte recovery.