LabDisk platform

Centrifugal microfluidics for automated analytics and diagnostics

With our LabDisk platform your diagnostic and analytic laboratory procedures can run fully automated on a cost-effective, CD-like disposable test element, the LabDisk.

The LabDisk platform makes automation solutions available for your assays within a short time, based on centrifugal microfluidic test elements, the "LabDisks". 

Using the LabDisks offers many advantages: 

  • Reduced personnel costs and reagent costs through automation in miniaturized, microfluidic standard
  • Complex analytical procedures can even be executed by personnel with minimal training; this means outsourcing to the so-called point-of-care is possible
  • Reproducibility is improved
  • The risk of cross-contamination is reduced

In addition to automation of standard laboratory procedures, application areas of the LabDisk platform also particularly include automation of molecular diagnostic tests, immunological tests, and protein-analytical tests. Application examples from the LabDisk platform portfolio include: 

  • Genotyping antibiotic resistance (MRSA) via nested PCR
  • Confirmation of KRAS mutations of tumor cell DNA as the basis for initiating personalized therapy  
  • Molecular-biological confirmation of pathogens in the event of neonatal sepsis as a fast alternative to blood culture. The integrated functionality in this regard includes sample preparation including cell lysis and DNA extraction, as well as downstream two-level Multiplex PCR. 
  • Confirmation of botulinum neurotoxins 

In this regard our service ranges from simulation-supported development of the fluidics to in-house polymer prototyping, and extends to proof-of-concept. In addition, for pilot validations or clinical studies we can also deliver larger quantities.

Contact


Dr. Katharina Dormanns
Hahn-Schickard,
Freiburg
Phone: +49 761 203-73293
Katharina.Dormanns@Hahn-Schickard.de
Directions

Dr. Nils Paust
Hahn-Schickard,
Freiburg
Phone: +49 761 203-73245
Nils.Paust@Hahn-Schickard.de
Directions

Check out how the LabDisk works

Proof-of-principle study

Read the article by GenomeWeb on our proof-of-principle, showing that a disc assay on the centrifugal-microfluidic platform enables rapid and portable molecular diagnostics: “German Team Develops Bacterial Pathogen Test on Prototype Qiagen Compact Analyzer” (PDF)

Microfluidic Automation in Molecular Diagnostics

Read our article on easy-to-use point-of-care tests in "BIOspektrum", October 2015, Volume 21, Issue 6, pp 622-624