Diagnostics platform for single-cell analysis Antibiotic-resistant bacteria

As part of our current research project, we are developing a mobile diagnostic platform for the detection of resistant pathogens (MRSA) at the point-of-care. By separating the microorganisms into droplets it is possible to conduct an analysis at the singl

The combination of digital amplification techniques with centrifugal microfluidics makes it possible to perform a quick one-site diagnosis. Thanks to our new approach to the integrated and automated analysis of sample material, individual cells are examined for their antibiotic resistance. A nasal swab is taken as a sample and inserted into a microfluidic cartridge. Individual bacteria are broken down into droplets, which allows infectious agents and their degree of antibiotic resistance to be detected at the same time. This classification makes it possible to perform specific procedures for the respective patient. The result can be determined within 40 minutes by using an isothermal detection reaction (RPA).

MRSA screening at the point of care

The goal of point-of-care diagnostics is to detect disease-relevant biomarkers reliably, quickly and easily. In addition, the droplet-based approach provides the added value of an analysis that is based on single cells.
Our interdisciplinary team of scientists and engineers, together with our partners from the Innovation Alliance for Baden-Württemberg (innBW), is developing a complete system consisting of a detection reaction, microfluidic cartridge, processing unit, and scalable production technologies.

Your partner for the development of integrated detection procedures

Are you interested in single-cell analyses and would you like to become more familiar with our platform? Are you looking for a partner to implement your detection procedure? Then get in touch with us.
We are always looking for new project partners and would gladly support you in the development and application of new test systems.

You might also be interested in: