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Holistic sepsis diagnostics and management through combined molecular biology and immunology testing on an integrated, automated platform for an improved and personalized therapeutic approach.
Hahn-Schickard coordinates the “Zukunftscluster nanodiag BW” together with the University of Freiburg. As part of the German federal government's "Clusters4Future" initiative, the Hahn-Schickard sites in Freiburg and Villingen-Schwenningen are involved in several scientific and strategic projects.
The aim of this project is the development of a platform for molecular diagnostic characterization of the immune response in viral diseases from blood serum. The platform shall be usable for high throughput professional laboratory diagnostics as well as decentralized at the point of care.
The selective organoid handling platform (SpheroPro) developed in ADAPT will be extended in ADAPT-2 to include an AI-assisted selection of suitable 3D cell culture models and a 3D imaging module based on holographic tomography for non-invasive and label-free analysis of organoids and spheroids.
The earliest possible diagnosis of cancer and the detection of therapy resistance are of utmost importance in order to maximize the survival chances of those affected. In the EV-Surf project, a new method for diagnosing cancers based on liquid biopsies is being researched.
The aim of the project is to make proteome data usable for the stratification of clear cell renal carcinoma patients and thus maximise the chances of therapeutic success.
Within the project LiquidXtractPT, a sustainably adaptable robotic platform for microfluidic cancer diagnosis in bodily fluids like blood is being developed. The prototype will be validated in two clinical pilot studies upon construction.
This cooperation project between Hahn-Schickard and the University of Freiburg investigates the continuous program verification for interface specifications during incremental software development to avoid serious programming errors in embedded software.
Mit SmaC soll eine integrative und gleichzeitig erweiterbare Kooperationsbasis geschaffen werden, welche Firmen, Entwicklern, Dienstleistern und auch Endanwendern ermöglicht neue Ideen im Smart Home-Bereich und ähnlichen Geschäftsfeldern zu entwickeln, realisieren, evaluieren und letztendlich zu erleben.
The project goal is to enable the use of protein profiles from samples with few cells for drug development. For this purpose, a workflow consisting of automated sample preparation, AI-supported image analysis and data evaluation as well as mass spectrometry will be developed and validated.
Within the scope of the project, a computer vision system for online measurement of the dosed volume in the form of a liquid jet is being developed. Compared to other volume measurement methods, the system based on a line scan camera convinces by the simplicity of the hardware and the contactless methodology.
The European Digital Innovation Hub Südwest (EDIH Südwest) is the central contact point in the southwest of Baden-Württemberg to support companies, the public sector, but also founders to dynamically respond to digital challenges and become more competitive.
The aim of the project is to evaluate an innovative MultiDetekt rapid test platform that enables the simultaneous detection of pathogens and local inflammatory markers in the wound.
We aim to address patient management and epidemic surveillance challenges in sub-Saharan Africa by converging four fit-for-purpose pillars: (1) innovative diagnostics, (2) capacity building, (3) enhancing human capital potential, and (4) adoption and implementation through stakeholder engagement.
Within the MeLB project the automation and standardization of liquid biopsy methods are investigated. Microfluidics methods are applied in order to isolate circulating tumor DNA (ctDNA) from blood samples, followed by parallelized quantification of DNA mutations using digital multiplex mediator probe PCR.