Multiplex analysis of mycobacterium tuberculosis in standard laboratory devices based on functional disposable cartridges (TB-Tube Multiplex)

This project aims towards an integrated microfluidic lab-on-a-chip platform for fast, reliable, contamination free, sensitive and economic diagnostics of tuberculosis, including genetic detection of resistance to antituberculous drugs.

To achieve this goal, biochemical processes are integrated into a centrifugal microfluidic cartridge that enables automated detection of the pathogen and of resistance to anti-tuberculous drugs in standard laboratory devices (centrifuge, PCR cycler). Hence, such diagnostic tests can be performed by non-experts using inexpensive laboratory equipment, in particular in poorly developed regions with a high prevalence of tuberculosis.

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PROJECT FOOTNOTE:

Sponsor: BMBF
Promoter: VDI Technologiezenturm GmbH
Funding Number: 13N13457
Duration: 01.05.2015 to 30.09.2018
Cooperation Partner: Robert Bosch GmbH, Hain-Lifescience GmbH, Gerbion GmbH, Braunform GmbH, IML Red GmbH
Maturity Level: Research

Contact

Steffen Zehnle
Hahn-Schickard,
Freiburg
Phone: 0761 203-73206
F: 0761 203-73299
Steffen.Zehnle@Hahn-Schickard.de
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