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Breath Gas Diagnostics: Point-of-Care Potential for Early Cancer Detection
The renowned journal ACS Sensors recently published promising results from a research team led by Prof. Dr. Boris Mizaikoff, director at Hahn-Schickard and professor at the Ulm University.
The article “Helicobacter pylori Breath Test via Mid-Infrared Sensor Technology” describes the development of an innovative sensor that enables the detection of specific molecules in liquids and gases. This sensor concept is based on miniaturized, substrate-integrated hollow waveguides, allowing highly sensitive and selective sample analysis.
One particularly promising application is in breath gas diagnostics. This technology could contribute to the early detection of diseases such as cancer by identifying specific biomarkers in exhaled air—a fast, non-invasive, and patient-friendly alternative to conventional diagnostic methods.
The miniaturization of this sensor concept has been jointly patented by the University of Ulm and Hahn-Schickard. The goal is to commercialize this technology through Hahn-Schickard, making innovative diagnostic tools more accessible for various applications.
This development is part of Hahn-Schickard’s ongoing research in breath gas analysis. Recently, a collaboration was announced with the company Breathlabs, which specializes in analyzing biomarkers in exhaled air. The partnership aims to transform innovative sensor technologies into market-ready solutions, further advancing non-invasive diagnostics.
The full publication is freely available: https://pubs.acs.org/doi/10.1021/acssensors.4c02785
The online news platform “Chemical & Engineering News” (c&en) picked up on this publication and interviewed Professor Boris Mizaikoff: https://cen.acs.org/analytical-chemistry/spectroscopy/mini-breath-sensor-detect-ulcer/103/web/2025/02
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Competences
- Analytical and bioanalytical chemistry
- Infrared spectroscopy and sensing
- Biomimetic molecular recognition architectures
- Integrated photonic systems