Intraoral drug dosing

Many medications can be absorbed more quickly and administered in a more targeted manner when taken via the oral mucosa rather than the stomach. Continuous dosage is particularly important for Parkinson's patients. For this reason, we have developed an intraoral medication dosing system called "BuccalDose" for liquid or water-soluble medications. As well as continuously releasing active components, it can also monitor the therapy via miniaturized RFID tags.
The osmotic delivery system is integrated with the patient's dental prosthesis in the form of a cartridge. The medication can be administered so much better and more efficiently, since the active component goes directly into the bloodstream. Parkinson's patients are currently the main application for this development, as they are particularly reliant on a continuous dosage of their medication. In advanced stages of the disease, the patient would have to take up to eight tablets per day with a very time-sensitive dosing regime (precise to within ten minutes). The patient only has to change the cartridge of the BuccalDose system once per day.

Miniature tag for monitored therapy
The system is connected via a tele-monitoring base station that determines the fill level of the cartridge. The RFID technology is used to identify the cartridge, which is held in place in the prosthesis using a magnet. The integrated miniaturized tag stores information such as medicine, dosing rate, manufacturer, or expiration date. "In addition to the fill level, the RFID reader can also be used to record this data in the base unit for future forwarding via a smartphone, for example, to a medical monitoring system. This is important for patient compliance: The doctor knows exactly whether the patient is continuing with their therapy, or he/she can adapt the therapy based on the data. The tiny cartridge can be exchanged quickly and safely in this useful device.